ADPS™ TERT Promoter Mutation Test Kit
- Detection target: 2 mutations in TERT promoter (C228T, C250T)
- Sample type: DNA extracted from FFPE, frozen, and fresh cancer tissue or liquid biopsy
- Detection Sensitivity:0.1%
- Detection Specificity: ≥ 99.0%
- Precision (% CV): ≤ 5% (CV, coefficient of variation)
INTENDED USE
The most common TERT mutations are in the promoter region, specifically C228T and C250T. These mutations result in increased TERT expression and telomerase activity, and aberrant activation of telomerase is associated with uncontrolled cell division and evasion of programmed cell death, ultimately enabling cancer progression.
The ADPS™ TERT Promoter Mutation Test Kit accurately detects two mutations in the TERT promoter, C228T and C250T, with a detection sensitivity of 0.05% and 0.07%, respectively. It is designed for testing both tissue and plasma samples with a single kit.
- Fast
- Sensitive
- Qualitative
- CE-IVD
Validated Instruments
