ADPS™ PIK3CA Mutation Test Kit
- Detection target: 11 mutations in PIK3CA exon 7, 9 and 20
- Sample type: DNA extracted from FFPE, frozen, and fresh cancer tissue or liquid biopsy
- Detection Sensitivity:0.03-0.5%
- Detection Specificity: ≥ 99.0%
- Precision (% CV): ≤ 5% (CV, coefficient of variation)
INTENDED USE
In breast cancer, PIK3CA is associated with resistance to hormone therapy and disease progression. PIK3CA gene mutations are observed in various cancer types, including colorectal, endometrial, lung, and breast cancer. About 70% of breast cancer patients are hormone receptor-positive (HR+), HER2 gene mutation-negative (-), and about 40% of these have PIK3CA gene mutations. PIK3CA mutation information can help guide the consideration of prescribing PIQRAY for breast cancer treatment.
The ADPS™ PIK3CA Mutation Test Kit detects 11 mutations in exons 7, 9, and 20 of the PIK3CA gene with a high sensitivity of up to 0.03%. It is designed for testing both tissue and plasma samples with a single kit.
- Fast
- Sensitive
- Qualitative
- CE-IVD
Validated Instruments
