ADPS™ EML4-ALK Gene Fusion Detection Kit
- Detection target: 97% of EML4-ALK variants in NSCLC (10 fusions)
- Sample type: DNA extracted from FFPE, frozen, and fresh cancer tissue or liquid biopsy
- Detection Sensitivity:50 copies/reaction
- Detection Specificity: ≥ 99.0%
- Precision (% CV): ≤ 5% (CV, coefficient of variation)
INTENDED USE
The EML4-ALK fusion gene is frequently found in non-small cell lung cancer (NSCLC). It is known to activate the downstream signaling pathway of receptor tyrosine kinase, leading to cancer development. The presence of the EML4-ALK fusion gene has been reported to correlate with the efficacy of ALK-targeted therapies.
The ADPS™ EML4-ALK Gene Fusion Detection Kit accurately detects 10 types of EML4-ALK fusion genes, representing approximately 97% of EML4-ALK cases found in NSCLC, at 50 copies per reaction. This is a one-step RT-qPCR test designed to test RNA extracted from both tissue and plasma samples with a single kit.
- Fast
- Sensitive
- Qualitative
- CE-IVD
- One-Step
- Turnaround Time 2 hrs
Validated Instruments
