ADPS™ ESR1 Mutation Test Kit
- Detection target: E380Q, Y537S and D538G mutations of ESR1 gene
- Sample type: DNA extracted from FFPE, frozen, and fresh cancer tissue or liquid biopsy
- Detection Sensitivity:E380Q: 0.03%, Y537S: 0.05% and D538G:0.08%%
- Detection Specificity: ≥ 99.0%
- Precision (% CV): ≤ 5% (CV, coefficient of variation)
INTENDED USE
The ESR1 gene encodes estrogen receptor alpha, which plays an important role in hormone-responsive breast cancer. The E380Q mutation may affect hormone binding, which may have implications for treatment strategies. The Y537S and D538G mutations can confer resistance to hormone therapy, posing challenges for clinical management.
In breast The ADPS™ ESR1 Mutation Test Kit detects three important mutations within the ESR1 gene, E380Q, Y537S, and D538G, with a high sensitivity of 0.03%, 0.05%, and 0.08%, respectively. It is designed for testing both tissue and plasma samples with a single kit. Analysis of ESR1 mutations plays an important role in breast cancer research and diagnosis.
- Fast
- Sensitive
- Qualitative
- CE-IVD
Validated Instruments
